By a News Reporter -- Current study results on nanoparticles have been published. According to news reporting from Tianjin, People's Republic of China, by NewsRx editors, research stated, "Lead sulphide nanoparticles (PbS NPs) are important nanoparticle materials which are widely used in photoelectric production, but their potential health hazard to the respiratory system is not clear. This study aimed to explore the possible mechanism of lung injury induced by PbS NPs."
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Our news journalists obtained a quote from the research team at Tianjin Union Medical Center, "Male SD rats were treated with nanoparticles of 60 nm and 30 nm lead sulphide. The main methods were detecting the vigour of superoxide dismutase (SOD) and total antioxidant capacity (T-AOC) and the content of malondialdehyde (MDA) in both blood and lung tissues and observing the pathological changes in lung tissue. PbS NPs suppressed the activity of SOD and T-AOC, and increased serum MDA content (P < 0.05); both effects were observed together in lung tissues of 30-nm group (P < 0.05) accompanied by an obviously inflammatory response. PbS NPs induced oxidative damage and inflammatory response in lung tissue, which may be an underlying mechanism for its pulmonary toxicity."
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According to the news editors, the research concluded: "Additionally, the toxicity of PbS NPs was closely related with the size of nanoparticles."